Trial intelligence / Profile preview

MSC-GRR2 trial of allogeneic mesenchymal stromal cells for steroid- and ruxolitinib-refractory acute graft-versus-host disease

2025-523448-10-00Phase 2Authorised

Sponsor
ASST Spedali Civili di Brescia
Start
Sep 2026
Modality
Stem Cell Therapies → Cell Therapies
Countries
1
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Overview

Phase 2, open-label, single-arm trial of mesenchymal stromal cells, ex vivo cultured in Acute Graft-Versus-Host Disease (aGvHD), sponsored by ASST Spedali Civili di Brescia. Primary endpoint: Overall response rate at day 28. Planned start Sep 2026; status: authorised.

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Drugs

mesenchymal stromal cells, ex vivo cultured
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Conditions

Acute Graft-Versus-Host Disease (aGvHD)

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