Trial intelligence / Profile preview

Targeted versus standard peri-operative antibiotic prophylaxis in carbapenemase-producing Enterobacterales-colonized liver transplant recipients

2025-523453-34-00Phase 3Authorised

Sponsor
Sant'Orsola-Malpighi University Hospital
Start
Aug 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of eravacycline, imipenem + cilastatin + relebactam, cefiderocol, ceftazidime + avibactam, meropenem + vaborbactam and 4 more in Enterobacterales infection, sponsored by Sant'Orsola-Malpighi University Hospital. Planned start Aug 2026; status: authorised.

02

Drugs

eravacyclineimipenem + cilastatin + relebactamcefiderocolceftazidime + avibactammeropenem + vaborbactam
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Conditions

Enterobacterales infection

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