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Asciminib in chronic phase CML with T315I mutation

2025-523491-23-00Phase 2Authorised

Sponsor
Friedrich Schiller University Jena
Start
Jun 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of asciminib in chronic myelogenous leukemia (CML), sponsored by Friedrich Schiller University Jena. Primary endpoint: MR2 rate at 12 months. Planned start Jun 2026; status: authorised.

02

Drugs

asciminib
03

Conditions

chronic myelogenous leukemia (CML)

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