Trial intelligence / Profile preview

Symbiotic-GU-08: PF-08634404 in locally advanced or metastatic renal cell carcinoma

2025-523524-53-00Phase 2Authorised

Sponsor
Pfizer
Start
Jun 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
7
01

Overview

Phase 2, open-label trial of PF-08634404 in renal cell carcinoma (RCC) (3 cohorts), sponsored by Pfizer. Primary endpoints: Cohort A: Confirmed objective response rate (ORR), Cohort A: Adverse events and 3 more. Planned start Jun 2026; status: authorised.

02

Drugs

PF-08634404
03

Conditions

renal cell carcinoma (RCC)

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