Trial intelligence / Profile preview

PF-08634404 plus sigvotatug vedotin in advanced non-small cell lung cancer

2025-523526-40-00Phase 2Authorised

Sponsor
Pfizer
Start
Aug 2026
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
9
01

Overview

Phase 2, open-label trial of PF-08634404 and sigvotatug vedotin in non-small cell lung cancer (NSCLC), sponsored by Pfizer. Primary endpoints: Adverse events, Dose-limiting toxicities and 1 more. Planned start Aug 2026; status: authorised.

02

Drugs

PF-08634404sigvotatug vedotin
03

Conditions

non-small cell lung cancer (NSCLC)

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