Trial intelligence / Profile preview

Dabogratinib (TYRA-300) in Low Grade Upper Tract Urothelial Carcinoma (SURF303)

2025-523539-20-00Phase 2Authorised

Sponsor
Tyra Biosciences
Start
Jul 2026
Modality
Small Molecules
Countries
5
01

Overview

Phase 2, open-label, single-arm trial of dabogratinib in transitional cell carcinoma (TCC), sponsored by Tyra Biosciences. Primary endpoints: Phase 2A complete response within 6 months, Recommended Phase 2B dose determination and 1 more. Planned start Jul 2026; status: authorised.

02

Drugs

dabogratinib
03

Conditions

transitional cell carcinoma (TCC)

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Available in the Gosset platform where reported.

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