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ROSETTA HCC-206: pumitamig alone or with ipilimumab in first-line advanced hepatocellular carcinoma

2025-523602-33-00Phase 2Authorised

Sponsor
Bristol Myers Squibb
Start
May 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
13
01

Overview

Phase 2, randomised, open-label trial in hepatocellular carcinoma (HCC) comparing Pumitamig monotherapy with Pumitamig + ipilimumab (2 arms). Primary endpoints: Phase 1 safety and tolerability and Phase 2 objective response rate. Planned start May 2026; status: authorised.

02

Drugs

pumitamigipilimumab
03

Conditions

hepatocellular carcinoma (HCC)

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