Trial intelligence / Profile preview

Adaptive Dose Escalation and Expansion Basket Trial of TGD001 in Immune-Mediated TTP and Other Thrombotic Microangiopathies

2025-523802-34-00Phase 2Authorised

Sponsor
TargED Biopharmaceuticals
Start
Oct 2026
Modality
Fab Fragments → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, scFv Fragments → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Nanobodies (VHH) → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
6
01

Overview

Phase 2, single-arm trial of TGD001 in thrombotic thrombocytopenic purpura (TTP) and thrombotic microangiopathies (TMA), sponsored by TargED Biopharmaceuticals. Primary endpoint: Treatment emergent adverse events. Planned start Oct 2026; status: authorised.

02

Drugs

TGD001
03

Conditions

thrombotic thrombocytopenic purpura (TTP)thrombotic microangiopathies (TMA)

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