Trial intelligence / Profile preview

COMBO-Seq trial in metastatic renal cell carcinoma

2025-523903-31-00Phase 3Authorised

Sponsor
Fondazione IRCCS - Istituto Nazionale dei Tumori di Milano
Start
Sep 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial of nivolumab, ipilimumab, pembrolizumab, axitinib, lenvatinib and 3 more in renal cell carcinoma (RCC) (3 arms), sponsored by Fondazione IRCCS - Istituto Nazionale dei Tumori di Milano. Primary endpoints: PFS-2 and Overall survival. Planned start Sep 2026; status: authorised.

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Drugs

nivolumabipilimumabpembrolizumabaxitiniblenvatinib
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Conditions

renal cell carcinoma (RCC)

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