Trial intelligence / Profile preview

CLEAR: lesigercept in adults with chronic spontaneous urticaria inadequately controlled by H1-antihistamines

2025-524006-14-00Phase 2Authorised

Sponsor
Yuhan
Start
Apr 2026
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Countries
5
01

Overview

Phase 2, randomised, double-blind trial in chronic idiopathic urticaria (CIU) comparing Lesigercept with Placebo (2 arms). Primary endpoint: Change from baseline in UAS7 at Week 12. Planned start Apr 2026; status: authorised.

02

Drugs

YH35324
03

Conditions

chronic idiopathic urticaria (CIU)

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