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ARMANI-2/ENGIC08 switch maintenance trial in advanced HER2-negative PD-L1-positive gastroesophageal adenocarcinoma

2025-524048-36-00Phase 3Authorised

Sponsor
G.O.N.O. - Gruppo Oncologico del Nord Ovest
Start
Aug 2026
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
3
01

Overview

Phase 3, randomised, open-label trial of paclitaxel, ramucirumab and tislelizumab in gastroesophageal junction adenocarcinoma (2 arms), sponsored by G.O.N.O. - Gruppo Oncologico del Nord Ovest. Primary endpoint: Progression-free survival. Planned start Aug 2026; status: authorised.

02

Drugs

paclitaxelramucirumabtislelizumab
03

Conditions

gastroesophageal junction adenocarcinoma

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