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Long-term extension study of SPY001-001, SPY002, and SPY003 alone or in combination in ulcerative colitis

2025-524640-35-00Phase 2Authorised

Sponsor
Spyre Therapeutics, Inc.
Start
Aug 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
37
01

Overview

Phase 2, open-label, single-arm trial of SPY001, SPY002 and SPY003 in autoimmune colitis, sponsored by Spyre Therapeutics, Inc. Primary endpoint: Incidence of treatment-emergent adverse events. Planned start Aug 2026; status: authorised.

02

Drugs

SPY001SPY002SPY003
03

Conditions

autoimmune colitis

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