Trial intelligence / Profile preview

Phase 3 placebo-controlled study of sapablursen in polycythemia vera

2025-524669-25-00Phase 3Authorised

Sponsor
Deciphera Pharmaceuticals
Start
Sep 2026
Modality
Gene Therapies, Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
20
01

Overview

Phase 3, randomised, double-blind trial in polycythemia vera (PV) comparing Sapablursen with Placebo (2 arms). Primary endpoint: Number of phlebotomies from Week 0 through Week 32 and hematocrit control through Week 32. Planned start Sep 2026; status: authorised.

02

Drugs

sapablursen
03

Conditions

polycythemia vera (PV)

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