Trial intelligence / Profile preview

Neoadjuvant amivantamab with lazertinib or chemotherapy in resectable EGFR-mutated non-small cell lung cancer

2025-524816-13-00Phase 2Authorised

Sponsor
Janssen Pharmaceutical
Start
Jul 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
6
01

Overview

Phase 2, open-label trial of amivantamab and lazertinib in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Janssen Pharmaceutical. Primary endpoint: Major pathological response. Planned start Jul 2026; status: authorised.

02

Drugs

amivantamablazertinib
03

Conditions

non-small cell lung cancer (NSCLC)

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