Trial intelligence / Profile preview

Doxy-WISE: Weekly versus event-driven doxycycline post-exposure prophylaxis for STI prevention in MSM and transgender women on HIV PrEP

2025-524823-34-00Phase 3Authorised

Sponsor
Institute of Tropical Medicine Antwerp
Start
Mar 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of doxycycline in sexually transmitted disease (STD), gonorrhea, Chlamydia trachomatis infection and 1 more (2 arms), sponsored by Institute of Tropical Medicine Antwerp. Primary endpoint: Primary: Incidence rate ratio of NG, CT, and TP infections. Planned start Mar 2026; status: authorised.

02

Drugs

doxycycline
03

Conditions

sexually transmitted disease (STD)gonorrheaChlamydia trachomatis infectionsyphilis

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