Trial intelligence / Profile preview

ODYSSEUS: pirtobrutinib plus epcoritamab for relapsed or refractory CLL/SLL

2025-524842-89-00Phase 2Authorised

Sponsor
HOVON
Start
Oct 2026
Modality
Small Molecules, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of pirtobrutinib and epcoritamab in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), sponsored by HOVON. Primary endpoints: Safety in safety run-in and Progression-free survival at 24 months. Planned start Oct 2026; status: authorised.

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Drugs

pirtobrutinibepcoritamab
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Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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