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DECREASE-IPC: De-escalating neoadjuvant chemoimmunotherapy in early triple-negative breast cancer

2025-525040-18-00Phase 2Authorised

Sponsor
Institut Paoli-Calmettes
Start
Jul 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, open-label, single-arm trial of pembrolizumab in triple-negative breast cancer (TNBC), sponsored by Institut Paoli-Calmettes. Primary endpoint: Pathologic complete response rate with MRI/biopsy correlation. Planned start Jul 2026; status: authorised.

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Drugs

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Conditions

triple-negative breast cancer (TNBC)

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