Trial intelligence / Profile preview

AMBIENCE trial of zenagamtide for cardiovascular risk reduction in overweight or obese adults with established atherosclerotic cardiovascular disease

2026-525182-53-00Phase 3Authorised

Sponsor
Novo Nordisk
Start
Oct 2026
Modality
Small Molecules, Peptides
Countries
25
01

Overview

Phase 3, randomised, double-blind trial in atherosclerotic disease, Overweight and obesity comparing Zenagamtide with Placebo (2 arms). Primary endpoint: 4-point major adverse cardiovascular events. Planned start Oct 2026; status: authorised.

02

Drugs

amycretin
03

Conditions

atherosclerotic diseaseOverweightobesity

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