Trial intelligence / Profile preview

DYNAMIC trial in oncogene-addicted metastatic non-small cell lung cancer

2026-525268-16-00Phase 3Authorised

Sponsor
University of Turin
Start
Oct 2026
Modality
Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of osimertinib, lazertinib, amivantamab, alectinib, brigatinib and 22 more in non-small cell lung cancer (NSCLC), sponsored by University of Turin. Primary endpoint: PFS2 at two years. Planned start Oct 2026; status: authorised.

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Drugs

osimertiniblazertinibamivantamabalectinibbrigatinib
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Conditions

non-small cell lung cancer (NSCLC)

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