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AMBITION 4: zenagamtide versus lower-dose semaglutide in type 2 diabetes

2026-525474-20-00Phase 3Authorised

Sponsor
Novo Nordisk
Start
Oct 2026
Modality
Recombinant Proteins and Enzymes, Peptides, Small Molecules
Countries
16
01

Overview

Phase 3, randomised trial in type 2 diabetes mellitus (T2DM) comparing Zenagamtide once weekly with Semaglutide once weekly (2 arms). Primary endpoint: Change in glycated haemoglobin A1c (HbA1c). Planned start Oct 2026; status: authorised.

02

Drugs

amycretinsemaglutide
03

Conditions

type 2 diabetes mellitus (T2DM)

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