Trial intelligence / Profile preview

ARV-6723 first-in-human phase 1/2 study in advanced solid tumors

2026-525614-57-00Phase 2Authorised

Sponsor
Arvinas
Start
Oct 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules
Countries
4
01

Overview

Phase 2, open-label trial of ARV-6723 and pembrolizumab in Non-hematologic malignancy and cancer (2 arms), sponsored by Arvinas. Primary endpoints: First cycle dose-limiting toxicities, Adverse events and 2 more. Planned start Oct 2026; status: authorised.

02

Drugs

03

Conditions

Non-hematologic malignancycancer

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