Trial intelligence / Profile preview

OCEAN-1 nalbuphine ER for chronic cough in idiopathic pulmonary fibrosis

2026-525877-38-00Phase 3Authorised

Sponsor
Trevi Therapeutics
Start
Oct 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
5
01

Overview

Phase 3, randomised, double-blind trial in chronic cough comparing Nalbuphine ER with Placebo to match nalbuphine ER (2 arms). Primary endpoint: Relative change from baseline in 24-hour cough frequency at Week 26. Planned start Oct 2026; status: authorised.

02

Drugs

nalbuphine
03

Conditions

chronic cough

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