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Petosemtamab plus mFOLFOX6 or FOLFIRI versus cetuximab plus mFOLFOX6 or FOLFIRI in first-line left-sided metastatic colorectal cancer

2026-525883-17-00Phase 3Authorised

Sponsor
Genmab
Start
Oct 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
26
01

Overview

Phase 3, randomised, open-label trial of petosemtamab in colorectal cancer (CRC) (4 arms), sponsored by Genmab. Primary endpoints: Progression-free survival and Objective response rate. Planned start Oct 2026; status: authorised.

02

Drugs

petosemtamab
03

Conditions

colorectal cancer (CRC)

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