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PAGER: Piperacillin/tazobactam vs ampicillin + gentamicin for community-acquired infection

2026-526131-20-00Phase 4Authorised

Sponsor
Capital Region of Denmark
Start
Aug 2026
Modality
Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 4, randomised trial in urosepsis, urinary tract infection (UTI), cystitis and 4 more comparing Piperacillin/tazobactam arm with Ampicillin + gentamicin arm (2 arms). Primary endpoints: 30-day all-cause mortality and 30-day acute kidney injury. Planned start Aug 2026; status: authorised.

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Drugs

piperacillin + tazobactamampicillin + gentamicin
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Conditions

urosepsisurinary tract infection (UTI)cystitispyelonephritispneumonia

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