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VIETS trial: VATS versus intrapleural enzymatic therapy for empyema

2026-526289-25-00Phase 4Authorised

Sponsor
Amsterdam University Medical Center
Start
Oct 2026
Modality
Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 4, randomised, open-label trial of dornase alfa and tissue-plasminogen activator in pleural abscess, Empyema Thoracis and pneumonia (2 arms), sponsored by Amsterdam University Medical Center. Primary endpoint: Length of hospital stay within first 30 days. Planned start Oct 2026; status: authorised.

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Drugs

dornase alfatissue-plasminogen activator
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Conditions

pleural abscessEmpyema Thoracispneumonia

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