Trial intelligence / Profile preview

Efimosfermin alfa dose-finding study in adults with alcohol-related liver disease

2026-526391-23-00Phase 2Authorised

Sponsor
GSK
Start
Oct 2026
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Countries
16
01

Overview

Phase 2, randomised, double-blind trial in alcoholic liver disease (ALD) comparing Efimosfermin alfa with Placebo (2 arms). Primary endpoints: Change from baseline in VCTE-LSM using FibroScan and Dual endpoint: change from baseline in VCTE-LSM using FibroScan and change from baseline in MELD. Planned start Oct 2026; status: authorised.

02

Drugs

efimosfermin
03

Conditions

alcoholic liver disease (ALD)

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