Trial intelligence / Profile preview

Pegcetacoplan for prevention of recurrent C3 glomerulopathy or primary immune-complex membranoproliferative glomerulonephritis after kidney transplantation

2026-526392-39-00Phase 3Authorised

Sponsor
Sobi
Start
Oct 2026
Modality
PEGylated Peptides → Modified Peptides → Peptides, Recombinant Proteins and Enzymes
Countries
10
01

Overview

Phase 3, open-label, single-arm trial of pegcetacoplan in Complement 3 glomerulopathy (C3G) and Primary immune complex membranoproliferative glomerulonephritis (MPGN), sponsored by Sobi. Primary endpoint: Occurrence of clinically significant recurrent disease within 2 years post-kidney transplantation. Planned start Oct 2026; status: authorised.

02

Drugs

pegcetacoplan
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Conditions

Complement 3 glomerulopathy (C3G)Primary immune complex membranoproliferative glomerulonephritis (MPGN)

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