Trial intelligence / Profile preview

ZODIAC: Denosumab vs Zoledronic acid for erosive hand osteoarthritis in patients with osteoporosis

2026-526828-41-00Phase 2Authorised

Sponsor
Azienda Ospedaliera Universitaria Integrata Verona
Start
Aug 2026
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, randomised trial of obodence and zoledronic acid in erosive hand osteoarthritis (EHOA) and osteoporosis (2 arms), sponsored by Azienda Ospedaliera Universitaria Integrata Verona. Primary endpoint: Change in total erosion volume at 12 months. Planned start Aug 2026; status: authorised.

02

Drugs

obodencezoledronic acid
03

Conditions

erosive hand osteoarthritis (EHOA)osteoporosis

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