Trial intelligence / Profile preview

TONIC trial of NFL-102 for tobacco and nicotine cessation

2026-527266-77-00Phase 2Authorised

Sponsor
NFL Biosciences
Start
Oct 2026
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2 trial of NFL-102 in nicotine dependence (2 arms), sponsored by NFL Biosciences. Primary endpoints: Safety and tolerability by dose level and 4-week continuous abstinence. Planned start Oct 2026; status: authorised.

02

Drugs

NFL-102
03

Conditions

nicotine dependence

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