Trial intelligence / Profile preview

CMF followed by tamoxifen versus tamoxifen alone in postmenopausal node-negative estrogen receptor-positive breast cancer

ACTRN12607000029493Phase 3Completed

Sponsor
International Breast Cancer Study Group
Start
Apr 1989
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of tamoxifen, cyclophosphamide, methotrexate and fluorouracil in breast cancer (2 arms), sponsored by International Breast Cancer Study Group. Primary endpoint: Disease-free survival. Started Apr 1989; status: completed.

02

Drugs

tamoxifencyclophosphamidemethotrexatefluorouracil
03

Conditions

breast cancer

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