Trial intelligence / Profile preview

Tocilizumab for prevention of acute graft-versus-host disease after HLA-matched allogeneic hematopoietic progenitor cell transplantation

ACTRN12614000266662Phase 3Recruiting

Sponsor
Royal Brisbane and Women's Hospital
Start
Apr 2014
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in graft-versus-host disease (GVHD) comparing Tocilizumab + standard transplant immunosuppression with Placebo + standard transplant immunosuppression (2 arms). Primary endpoint: Incidence of grade II-IV acute graft-versus-host disease. Started Apr 2014; status: recruiting.

02

Drugs

tocilizumab
03

Conditions

graft-versus-host disease (GVHD)

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