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Metformin for prevention of tamoxifen-associated endometrial changes
ACTRN12614000838617Phase 2Completed
- Sponsor
- Monash University
- Start
- Jul 2014
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 2, randomised, double-blind trial in endometrial cancer (EC) comparing Metformin + tamoxifen with Placebo + tamoxifen (2 arms). Primary endpoints: Expression of LKB1/AMPK pathway genes in endometrial biopsy tissue, Expression of mTOR-related genes in endometrial biopsy tissue and 1 more. Started Jul 2014; status: completed.
02
Drugs
metformin
03
Conditions
endometrial cancer (EC)
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