Trial intelligence / Profile preview

Olaparib with or without cyclophosphamide and durvalumab for recurrent ovarian, fallopian tube, or primary peritoneal cancer

ACTRN12618000686202Phase 2Completed

Sponsor
The University of Sydney
Start
May 2019
Modality
Small Molecules, PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of olaparib, durvalumab and cyclophosphamide in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC) (3 arms), sponsored by The University of Sydney. Primary endpoint: 36-week progression-free survival rate. Started May 2019; status: completed.

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Drugs

olaparibdurvalumabcyclophosphamide
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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