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Hyperbaric oxygen versus PENTOCLO for mandibular osteoradionecrosis
ACTRN12618001099213Phase 3Not yet recruiting
- Sponsor
- Dr Emma Lewis
- Start
- Jan 2019
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial of pentoxifylline, tocopherol and clodronate in Mandibular osteoradionecrosis (ORN) (2 arms), sponsored by Dr Emma Lewis. Primary endpoints: Improvement in mandibular osteoradionecrosis and Complete healing of mandibular osteoradionecrosis. Planned start Jan 2019; status: not yet recruiting.
02
Drugs
pentoxifyllinetocopherolclodronate
03
Conditions
Mandibular osteoradionecrosis (ORN)
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