Trial intelligence / Profile preview

Dexamethasone implant added to anti-VEGF for resistant neovascular age-related macular degeneration

ACTRN12618001102268Phase 4Completed

Sponsor
AOU Sassari
Start
Feb 2016
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 4, open-label trial of dexamethasone, ranibizumab and aflibercept in exudative macular degeneration and Subretinal neovascularization (2 arms), sponsored by AOU Sassari. Primary endpoint: Complete regression of intraretinal/subretinal fluid. Started Feb 2016; status: completed.

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Drugs

dexamethasoneranibizumabaflibercept
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Conditions

exudative macular degenerationSubretinal neovascularization

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