Trial intelligence / Profile preview

Durvalumab + tremelimumab with platinum-pemetrexed for EGFR-mutant advanced non-small cell lung cancer after EGFR TKI progression

ACTRN12618001742268Phase 2Completed

Sponsor
University of Sydney
Start
Apr 2019
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
2
01

Overview

Phase 2, open-label trial of durvalumab, tremelimumab, pemetrexed, cisplatin and carboplatin in non-small cell lung cancer (NSCLC) (2 cohorts), sponsored by University of Sydney. Primary endpoint: Objective tumour response rate by RECIST 1.1. Started Apr 2019; status: completed.

02

Drugs

durvalumabtremelimumabpemetrexedcisplatincarboplatin
03

Conditions

non-small cell lung cancer (NSCLC)

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