Trial intelligence / Profile preview

Radiotherapy plus PCV versus radiotherapy plus temozolomide for newly diagnosed 1p/19q-codeleted IDH-mutant glioma

ACTRN12620000402943Phase 3Withdrawn

Sponsor
Cancer and Leukemia Group B
Start
Oct 2022
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
7
01

Overview

Phase 3, randomised, open-label trial of temozolomide, procarbazine, lomustine and vincristine in glioma, anaplastic glioma and low-grade glioma (LGG) (2 arms), sponsored by Cancer and Leukemia Group B. Primary endpoint: Progression-free survival. Planned start Oct 2022; status: withdrawn.

02

Drugs

temozolomideprocarbazinelomustinevincristine
03

Conditions

gliomaanaplastic gliomalow-grade glioma (LGG)

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