Trial intelligence / Profile preview

Pentosan polysulfate sodium for knee osteoarthritis biomarkers and symptoms

ACTRN12621000136808Phase 2Recruiting

Sponsor
Paradigm Biopharmaceuticals
Start
Apr 2021
Modality
Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in knee osteoarthritis (OA) comparing PPS twice weekly, PPS once weekly plus placebo once weekly and Placebo twice weekly (3 arms). Primary endpoints: Change in synovial fluid biomarkers associated with inflammation and Change in synovial fluid biomarkers associated with osteoarthritis disease progression. Started Apr 2021; status: recruiting.

02

Drugs

pentosan polysulfate sodium
03

Conditions

knee osteoarthritis (OA)

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