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Dexamethasone vs placebo to reduce acute phase reaction after first zoledronic acid infusion

ACTRN12621000415808Phase 4Completed

Sponsor
Bone & Joint Research Group
Start
May 2021
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, double-blind trial in osteoporosis and Paget's disease of bone comparing Dexamethasone + zoledronic acid with Placebo + zoledronic acid (2 arms). Primary endpoint: Between-group difference in temperature change from baseline. Started May 2021; status: completed.

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Drugs

dexamethasone
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Conditions

osteoporosisPaget's disease of bone

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