Trial intelligence / Profile preview

PRIME005 in advanced melanoma after failure of prior anti-PD1 + anti-CTLA4 immunotherapy

ACTRN12621001155886Phase 2Active, not recruiting

Sponsor
University of Newcastle
Start
Sep 2021
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of azacitidine, carboplatin, ipilimumab and nivolumab in melanoma (2 arms), sponsored by University of Newcastle. Primary endpoints: Clinical benefit rate, Dose-limiting toxicity and 1 more. Started Sep 2021; status: active, not recruiting.

02

Drugs

azacitidinecarboplatinipilimumabnivolumab
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Conditions

melanoma

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