Trial intelligence / Profile preview

Pembrolizumab plus R-CHOP for primary mediastinal B-cell lymphoma

ACTRN12621001529831Phase 2Active, not recruiting

Sponsor
Australasian Leukaemia & Lymphoma Group
Start
Jan 2023
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
2
01

Overview

Phase 2, open-label, single-arm trial of pembrolizumab, rituximab, cyclophosphamide, doxorubicin, vincristine and 1 more in primary mediastinal large B-cell lymphoma (PMBCL), sponsored by Australasian Leukaemia & Lymphoma Group. Primary endpoint: Event-free survival. Started Jan 2023; status: active, not recruiting.

02

Drugs

pembrolizumabrituximabcyclophosphamidedoxorubicinvincristine
03

Conditions

primary mediastinal large B-cell lymphoma (PMBCL)

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