Trial intelligence / Profile preview

Semaglutide for post-liver transplant hepatic steatosis and obesity

ACTRN12621001739808Phase 3Not yet recruiting

Sponsor
Novo Nordisk
Start
May 2026
Modality
Recombinant Proteins and Enzymes, Peptides
Countries
1
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Overview

Phase 3, randomised, double-blind trial in metabolic dysfunction-associated steatotic liver disease (MASLD), obesity and cardiometabolic risk (CMR) comparing Semaglutide with Placebo (2 arms). Primary endpoint: Proportion of participants with at least 30% reduction in liver fat fraction by MRI-PDFF. Planned start May 2026; status: not yet recruiting.

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Drugs

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Conditions

metabolic dysfunction-associated steatotic liver disease (MASLD)obesitycardiometabolic risk (CMR)

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