Trial intelligence / Profile preview

ALLG AMLM28 ADAPT platform trial in newly diagnosed AML unfit for intensive chemotherapy

ACTRN12623000900617Phase 2Recruiting

Sponsor
Australasian Leukaemia & Lymphoma Group
Start
May 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of venetoclax and azacitidine in acute myeloid leukemia (AML) (5 arms), sponsored by Australasian Leukaemia & Lymphoma Group. Primary endpoint: Development of centralized MRD monitoring network. Started May 2026; status: recruiting.

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Drugs

venetoclaxazacitidine
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Conditions

acute myeloid leukemia (AML)

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