Trial intelligence / Profile preview

E-EDV-D682 + EDV-GC in advanced EGFR-expressing solid tumors

ACTRN12625000203459Phase 2Recruiting

Sponsor
EnGeneIC
Start
Apr 2025
Modality
Nanoparticles → Drug Delivery Systems, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of EGFR(V)-EDV-PNU and EDV-GC in Nonhematologic neoplasms, non-small cell lung cancer (NSCLC), mesothelioma and 8 more, sponsored by EnGeneIC. Primary endpoints: Safety and tolerability of E-EDV-D682/GC, Overall survival and 1 more. Started Apr 2025; status: recruiting.

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Drugs

EGFR(V)-EDV-PNUEDV-GC
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Conditions

Nonhematologic neoplasmsnon-small cell lung cancer (NSCLC)mesotheliomabladder cancerkidney cancer

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