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Imetelstat in high-risk MDS or AML after HMA-based therapy failure
ACTRN12625000226404Phase 2Completed
- Sponsor
- Australasian Leukaemia & Lymphoma Group
- Start
- Aug 2023
- Modality
- Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Countries
- 3
01
Overview
Phase 2, open-label, single-arm trial of imetelstat in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), sponsored by Australasian Leukaemia & Lymphoma Group. Primary endpoint: Overall response rate. Started Aug 2023; status: completed.
02
Drugs
imetelstat
03
Conditions
myelodysplastic syndrome (MDS)acute myeloid leukemia (AML)
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