Trial intelligence / Profile preview

Lenzilumab + azacitidine for VEXAS syndrome

ACTRN12625000619448Phase 2Not yet recruiting

Sponsor
South Australian Health and Medical Research Institute
Start
Aug 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of lenzilumab and azacitidine in VEXAS syndrome (VEXAS), sponsored by South Australian Health and Medical Research Institute. Primary endpoint: Safety and tolerability. Planned start Aug 2025; status: not yet recruiting.

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Drugs

lenzilumabazacitidine
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Conditions

VEXAS syndrome (VEXAS)

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