Trial intelligence / Profile preview

Sildenafil for symptomatic INOCA

ACTRN12625001161415Phase 3Not yet recruiting

Sponsor
Sydney Local Health District
Start
Nov 2025
Modality
Small Molecules
Countries
1
01

Overview

Phase 3, randomised trial in Ischemia with non-obstructed coronary arteries (INOCA), microvascular angina (MVA), Coronary vasospasm (CAS) and 1 more comparing Sildenafil with Placebo (2 arms). Primary endpoint: Effects of sildenafil on coronary endothelium-dependent and endothelium-independent microvascular dysfunction. Planned start Nov 2025; status: not yet recruiting.

02

Drugs

sildenafil
03

Conditions

Ischemia with non-obstructed coronary arteries (INOCA)microvascular angina (MVA)Coronary vasospasm (CAS)non-obstructive coronary artery disease

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