Trial intelligence / Profile preview

Dexmedetomidine added to ropivacaine for posterior quadratus lumborum block in laparoscopic colorectal surgery

ACTRN12626000090314Phase 4Not yet recruiting

Sponsor
University Hospital Center Sestre milosrdnice
Start
Mar 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 4, randomised, double-blind trial in colorectal cancer (CRC) comparing Ropivacaine + dexmedetomidine with Ropivacaine alone (2 arms). Primary endpoint: Total opioid requirement in the first 24 hours after laparoscopic colorectal surgery with the use of dexmedetomidine as an adjuvant in posterior quadratus lumborum block (QLB2). Planned start Mar 2026; status: not yet recruiting.

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Drugs

dexmedetomidineropivacaine
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Conditions

colorectal cancer (CRC)

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