Trial intelligence / Profile preview

SIR2501 in ALS and paclitaxel-associated CIPN risk

ACTRN12626000441314Phase 2Recruiting

Sponsor
Sironax
Start
Jan 2026
Modality
Small Molecules
Countries
2
01

Overview

Phase 2, open-label trial of SIR2501 in amyotrophic lateral sclerosis (ALS) and chemotherapy-induced peripheral neuropathy (CIPN) (4 arms), sponsored by Sironax. Primary endpoints: Incidence of dose-limiting toxicities, Change in Amyotrophic Lateral Sclerosis Functional Rating Scale Revised score and 1 more. Started Jan 2026; status: recruiting.

02

Drugs

SIR2501
03

Conditions

amyotrophic lateral sclerosis (ALS)chemotherapy-induced peripheral neuropathy (CIPN)

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