Trial intelligence / Profile preview

Aldosterone antagonist for diastolic dysfunction in hypertension with LV hypertrophy

ChiCTR-IPR-16009507Phase 4Recruiting

Sponsor
Shanghai Ninth People's Hospital
Start
Oct 2016
Modality
Small Molecules
Countries
1
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Overview

Phase 4, randomised trial in heart failure with preserved ejection fraction (HFpEF), hypertension (HTN) and left ventricular hypertrophy (LVH) comparing Spironolactone with Placebo (2 arms). Primary endpoint: Left ventricular diastolic function (E/E’ by tissue Doppler imaging). Started Oct 2016; status: recruiting.

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Drugs

spironolactone
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Conditions

heart failure with preserved ejection fraction (HFpEF)hypertension (HTN)left ventricular hypertrophy (LVH)

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